This course covers the structure, architecture, design and methods of Health Information Systems implementation and their applications towards improving the quality of care. Health Informatics (HI) focuses on the application of information technology (IT) to the field of medicine to improve individual and population healthcare delivery, education and research. This extensively course reflects the current knowledge in Health Informatics and provides learning objectives, key points, case studies and references. Topics include: Healthcare Data, Information, and Knowledge; Electronic Health Records, Practice Management Systems; Architectures of Information Systems; Consumer HI; Mobile Technology; Online Medical Resources; Search Engines; Evidence-Based Medicine and Clinical Practice Guidelines; Disease Management and Registries; Quality Improvement Strategies; Patient Safety; Picture Archiving and Communication Systems; Bioinformatics; Public HI; E-Research.