This course consists of four main parts. The first part introduces climate change by answering the question ?How and why the climate is changing?. The second part focuses on the impact of climate change on the human health and on the related sectors that are important for the human life including water and agriculture. Climate change hazards, such as drought, floods, heat waves and their impacts on health will be introduced. In the third part, the focus will be on responses and adaptation to climate change. Several examples on climate resilient adaptation and mitigation measures will be addressed for water, health and agriculture sectors. In the last part, climate change modelling, climate change scenarios development and vulnerability assessment will be introduced