This course will cover details of the aspects of clinical trials and the complex ethical challenges with specific attention to RCR ethical issues in the industry. These include Clinical Trials Methodology, Ethics of Clinical Trials design, Ethics of Research Participants Recruitments, Risk-benefit Assessment, Informed Consent in Research, Data Safety Monitoring Boards, Multi-national Research, Clinical Investigator Behavior, Independent Review and Oversight, and Research on Special Populations. The main aim of the course is to allow students to have expertise in clinical trials ethics, especially in relation to drug development for prevention and treatment.