This course provides graduate nursing students with the opportunity to design, implement, and evaluate a practice-based clinical project that addresses a significant problem in healthcare or nursing practice. It emphasizes the translation of evidence into practice, leadership in clinical improvement, and the use of informatics and digital innovation, including artificial intelligence (AI)?supported tools, to enhance patient outcomes and organizational effectiveness. Throughout the course, students practice the role of the nursing researcher, applying advanced skills in critical thinking, research appraisal, data management, and project evaluation. Ethical standards, professionalism, and scholarly communication are emphasized at every stage. The final product of this course is a comprehensive clinical project report and oral presentation demonstrating the integration of evidence, practice, and innovation.