This course explores the fundamental and advanced concepts of antimicrobial resistance (AMR), its drivers, and global impact. Students will learn how bacteria develop and transmit resistance, study key mechanisms (enzymatic inactivation, efflux pumps, target modification), and train in phenotypic and molecular laboratory detection methods. Practical sessions emphasize antimicrobial susceptibility testing (AST) and resistance mechanism detection using conventional microbiology. The course also introduces bioinformatics tools for whole genome sequencing (WGS) analysis to detect resistance genes in silico, focusing on simple and accessible platforms.