This premedical general course of physics introduces the students to mechanical aspects of physics such as force, gravitation, Density, Newton?s first and third laws, equilibrium, Newton?s second law, Friction, torque, static equilibrium, center of gravity, Levers and muscles. Elasticity including Stress, Strain and Young?s Modulus are also presented. The students will understand the temperature scales, molecular masses, pressure, and the principle of ideal gas law. Human metabolisms, Radiation, Temperature regulation in warm ? blooded animals are other phrases need for the premedical student. Fluid mechanics including Archimedes? Principle, Continuity Equation, Streamline Flow, and Bernoulli?s Equation will be presented. The role of gravity in the circulation, Blood pressure using the sphygmomanometer will be given. Viscosity, Flow in the circulatory systems and Centrifugation are applications on fluids. The structure of nerve cells, the resistance and the capacitance of an axon, electroencephalography and electrocardiograph are given as applications. Sound waves including the nature and speed of sound, sound detectors, auditory response, and ultrasound are presented. Light including the index of reflection, reflection and refraction, total internal reflection principles will be given. Concentration on the X-Ray diffraction and the structure of biological molecules are given as applications. In geometric optics; Mirrors, lenses, and the power of the lenses will be given. The aberrations, human eye, tomography, imaging a slice, optical defects of the eye will be given as applications. The students will handle some applications in radioactivity in details, half-life, dating in archaeology and geology, radioactive decays as part of their knowledge in physical phenomena. Ionizing radiation will also be explained including the interaction radiation with matter, radiation units, harmful of radiation, chronic radiation exposure and radiation in medicine.