Abstract:  

Rhinocerebral mucormycosis (RCM) is a rare opportunistic infection, affecting almost exclusively patients with immunocompromised status, and represents the third most common angio-invasive fungal infection after candidiasis and aspergillosis. It is considered one of the most important medical complications in immunocompromised patients. In spite of this, we report here a case of a RCM in an immunocompetent 48 year-old male who was referred to King Abdullah University Hospital (KAUH) in March 2013 from Jordan University of Science and Technology primary health care center (JUST primary health care center) as a case of worsening bacterial sinusitis, which was managed as an inpatient case with multiple endoscopic debridement surgery and intravenous amphotericin B with good outcome.